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The relative frequencies of T Helper subpopulation and Treg lymphocyte in the different groups of subjects. Bar plot representing the median and 95% IC of Th cells relative frequencies in non vaccinated (VAC0) or vaccinated (VAC2 + 3) ( a ) or depending on the number of doses ( b ). Pie-chart showing the relative frequency of CD19 + B cells, CD8 and <t>CD4</t> <t>T-cells</t> sub-populations on CD3 + lymphocytes in VAC0, VAC2 and VAC3 ( c ). p-alues were obtained using non-parametric Spearman test. Levels of statistical significance was set at p < 0.05
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The relative frequencies of T Helper subpopulation and Treg lymphocyte in the different groups of subjects. Bar plot representing the median and 95% IC of Th cells relative frequencies in non vaccinated (VAC0) or vaccinated (VAC2 + 3) ( a ) or depending on the number of doses ( b ). Pie-chart showing the relative frequency of CD19 + B cells, CD8 and CD4 T-cells sub-populations on CD3 + lymphocytes in VAC0, VAC2 and VAC3 ( c ). p-alues were obtained using non-parametric Spearman test. Levels of statistical significance was set at p < 0.05

Journal: Journal of Translational Medicine

Article Title: Immune signature in vaccinated versus non-vaccinated aged people with COVID-19 pneumonia

doi: 10.1186/s12967-024-05556-2

Figure Lengend Snippet: The relative frequencies of T Helper subpopulation and Treg lymphocyte in the different groups of subjects. Bar plot representing the median and 95% IC of Th cells relative frequencies in non vaccinated (VAC0) or vaccinated (VAC2 + 3) ( a ) or depending on the number of doses ( b ). Pie-chart showing the relative frequency of CD19 + B cells, CD8 and CD4 T-cells sub-populations on CD3 + lymphocytes in VAC0, VAC2 and VAC3 ( c ). p-alues were obtained using non-parametric Spearman test. Levels of statistical significance was set at p < 0.05

Article Snippet: For B and T cell populations DURAClone IM B cell tube and DURAClone IM T cell (both from Beckman Coulter, Research Use Only RUO) were used as we previously described [ ].

Techniques: